Publications

IMSD Undergraduate

Berenz EC, McNett S, Rappaport LM, Vujanovic AA, Viana AG, Dick D, Amstadter AB. Age of alcohol use initiation and psychiatric symptoms among yound adult trauma survivors. Addict Behav. 2019 Jan; 88:150-156. doi: 10.1016/j.addbeh.2018.08.022. Epub 2018 Aug 23. PubMed PMID: 30195854.

DeVault L, Li T, Izabel S, Thompson-Peer KL, Jan LY, Jan YN. Dendrite regeneration of adult Drosophila sensory neurons diminishes with aging and is inhibited by epidermal-derived matrix metalloproteinase 2. Genes Dev. 2018 Mar 1;32(5-6):402-414. doi: 10.1101/gad.308270.117. Epub 2018 Mar 21. PubMed PMID: 29563183.

Pearse DD, Bastidas J, Izabel SS, Ghosh M. Schwann Cell Transplantation Subdues the Pro-Inflammatory Innate Immune Cell Response after Spinal Cord Injury. Int J Mol Sci. 2018 Aug 28;19(9). pii: E2550. doi: 10.3390/ijms19092550. PubMed PMID: 30154346

Wetzel PA, Lindblad AS, Raizada H, James N, Multaya C, Kannan MA, Villamar Z, Gitchel GT, Weaver LK. Eye Tracking Results in Postconcussive Syndrome Versus Normative Participants. Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):4011-4019. doi: 10.1167/iovs.18-23815. PubMed PMID: 30098189.

Abrams JS, Howe SE, Becerra N, Kohli P, Konjufca V. Immunogenicity of antigen-conjugated biodegradable polydiacetylene liposomes administered mucosally. J Biomed Mater Res A. 2017 Feb;105(2):557-565. doi: 10.1002/jbm.a.35938. Epub 2016 Nov 5. PubMed PMID: 27750375.

Daniel R, Wu Q, Williams V, Clark G, Guruli G, Zehner Z. A Panel of MicroRNAs as Diagnostic Biomarkers for the Identification of Prostate Cancer. Int J Mol Sci. 2017 Jun 16;18(6). pii:E1281. doi: 10.3390/ijms18061281. PubMed PMID: 286261736

Griggs LA, Hassan NT, Malik RS, Griffin BP, Martinez BA, Elmore LW, Lemmon CA. Fibronectin fibrils regulate TGF-β1-induced Epithelial-Mesenchymal Transition. Matrix Biol. 2017 Jul;60-61:157-175. doi: 10.1016/j.matbio.2017.01.001. Epub 2016 Oct 6. PubMed PMID: 28109697.

Tsotsoros SD, Lutz PB, Daniel AG, Peterson EJ, de Paiva REF, Rivera E, Qu Y, Bayse CA, Farrell NP. Enhancement of the physicochemical properties of [Pt(dien).(nucleobase)]2+ for HIVNCp7 targeting. Chem Sci. 2017 Feb 1;8(2):1269-1281. doi: 10.1039/c6sc03445d. Epub 2016 Oct 6. PubMed PMID: 28451269.

Kolawole EM, McLeod JJ, Ndaw V, Abebayehu D, Barnstein BO, Faber T, Spence AJ, Taruselli M, Paranjape A, Haque TT, Qayum AA, Kazmi QA, Wijesinghe DS, Sturgill JL, Chalfant CE, Straus DB, Oskeritzian CA, Ryan JJ. Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects. J Immunol. 2016 Feb 15;196(4):1461-70. doi: 10.4049/jimmunol.1501932. Epub 2016 Jan 15. PubMed PMID: 26773154.

Seashols-Williams S, Lewis C, Calloway C, Peace N, Harrison A, Hayes-Nash C, Fleming S, Wu Q, Zehner ZE. High-throughput miRNA sequencing and identification of biomarkers for forensically relevant biological fluids. Electrophoresis. 2016 Oct;37(21):2780-2788. doi: 10.1002/elps.201600258. Epub 2016 Oct 7. PubMed PMID: 27557737.

Seashols-Williams SJ, Budd W, Clark GC, Wu Q, Daniel R, Dragoescu E, Zehner ZE. miR-9 Acts as an OncomiR in Prostate Cancer through Multiple Pathways That Drive Tumour Progression and Metastasis. PLoS One. 2016 Jul 22;11(7):e0159601. doi: 10.1371/journal.pone.0159601. eCollection 2016. PubMed PMID: 27447934.

Qayum AA, Paranjape A, Abebayehu D, Kolawole EM, Haque TT, McLeod JJ, Spence AJ, Caslin HL, Taruselli MT, Chumanevich AP, Baker B, Oskeritzian CA, Ryan JJ. IL-10-Induced miR-155 Targets SOCS1 To Enhance IgE-Mediated Mast Cell Function. J Immunol. 2016 Jun 1;196(11):4457-67. doi: 10.4049/jimmunol.1502240. Epub 2016 Apr 29. PubMed PMID: 27183599.

Durrant DE, Das A, Dyer S, Tavallai S, Dent P, Kukreja RC. Targeted Inhibition of Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Sensitizes Pancreatic Cancer Cells to Doxorubicin without Exacerbating Cardiac Toxicity. Mol Pharmacol. 2015 Sep;88(3):512-23. doi: 10.1124/mol.115.099143. Epub 2015 Jun 22. PubMed PMID: 26101222.

Lizhnyak PN, Yohannes H, Ottens AK. Neuroproteome Dynamics in Modeled Brain Injury: A Systems Neurobiology Perspective. In: Kobeissy FH, editor. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects. Boca Raton (FL): CRC Press/Taylor & Francis; 2015. Chapter 27. PubMed PMID: 26269918.

Pope WH, Bowman CA, Russell DA, Jacobs-Sera D, Asai DJ, Cresawn SG, Jacobs WR, Hendrix RW, Lawrence JG, Hatfull GF; Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science; Phage Hunters Integrating Research and Education; Mycobacterial Genetics Course. Whole genome comparison of a large collection of mycobacteriophages reveals a continuum of phage genetic diversity. Elife. 2015 Apr 28;4:e06416. doi: 10.7554/eLife.06416. PubMed PMID: 25919952.

Kim EY, Sturgill JL, Hait NC, Avni D, Valencia EC, Maceyka M, Lima S, Allegood J, Huang WC, Zhang S, Milstein S, Conrad D, Speigel S. Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching. FASEB J. 2014 Oct;28(10:4347-58.PubMed PMID: 25002116; PubMed Central PMCID: 4202100.

Chiplunkar AR, Lung TK, Alhashem Y, Koppenhaver BA, Salloum FA, Kukreja RC, Haar JL, Lloyd JA. Krüppel-like factor 2 is required for normal mouse cardiac development. PLoS One. 2013;8(2):e54891. doi: 10. 137/journal.pone.0054891. Epub 2013 Feb 14. PubMed PMID: 23457456; PubMed Central PMCID: PMC3573061.

Fuller BF, Cortes DF, Landis MK, Yohannes H, Griffin HE, Stafflinger JE, Bowers MS, Lewis MH, Fox MA, Ottens AK. Exposure of rats to environmental tobacco smoke during Cerebellar development alters behavior and perturbs mitochondrial energetics.Environ Health Perspect. 2012 Dec;120(12):1684-91. doi: 10. 1289/ehp. 1104857. Epub 2012 Sep 26. PubMed PMID: 23014793; PubMed Central PMCID: PMC3548280.

IMSD Graduate

Dawson A, Wolstenholme JT, Roni MA, Campbell VC, Jackson A, Slater C, Bagdas D, Perez EE, Bettinger JC, De Biasi M, Miles MF, Damaj MI. Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice. Neuropharmacology. 2018 Aug;138:341-348. doi: 10.1016/j.neuropharm.2018.06.031. Epub 2018 Jan 23. PubMed PMID: 29944862.

Wiley JL, Owens RA, Lichtman AH. Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids. Curr Top Behav Neurosci. 2018;39:153-173. doi: 10.1007/7854_2016_24. PubMed PMID: 27278640.

Abebayehu D, Spence AJ, Qayum AA, Taruselli MT, McLeod JJ, Caslin HL, Chumanevich AP, Kolawole EM, Paranjape A, Baker B, Ndaw VS, Barnstein BO, Oskeritzian CA, Sell SA, Ryan JJ. Lactic Acid Suppresses IL-33-Mediated Mast Cell Inflammatory Responses via Hypoxia-Inducible Factor-1α-Dependent miR-155 Suppression. J Immunol. 2016 Oct 1;197(7):2909-17. doi: 10.4049/jimmunol.1600651. Epub 2016 Aug 24. PubMed PMID: 27559047.

Guedia J, Brun P, Bhave S, Fitting S, Kang M, Dewey WL, Hauser KF, Akbarali HI. HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system. Sci Rep. 2016 Aug 5;6:31203. doi: 10.1038/srep31203. PubMed PMID: 27491828.

Owens RA, Ignatowska-Jankowska B, Mustafa M, Beardsley PM, Wiley JL, Jali A, Selley DE, Niphakis MJ, Cravatt BF, Lichtman AH. Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice. J Pharmacol Exp Ther. 2016 Aug;358(2):306-14. doi: 10.1124/jpet.115.229492. Epub 2016 Jun 15. PubMed PMID: 27307500.

Paranjape A, Chernushevich O, Qayum AA, Spence AJ, Taruselli MT, Abebayehu D, Barnstein BO, McLeod JJ, Baker B, Bajaj GS, Chumanevich AP, Oskeritzian CA, Ryan JJ. Dexamethasone rapidly suppresses IL-33-stimulated mast cell function by blocking transcription factor activity. J Leukoc Biol. 2016 Dec;100(6):1395-1404. Epub 2016 Jul 21. PubMed PMID: 27443878.

Randolph AL, Mokrab Y, Bennett AL, Sansom MS, Ramsey IS. Proton currents constrain structural models of voltage sensor activation. Elife. 2016 Aug 30;5. pii: e18017. doi: 10.7554/eLife.18017. PubMed PMID: 27572256.

Allen-Daniels MJ, Serrano MG, Pflugner LP, Fettweis JM, Prestosa MA, Koparde VN, Brooks JP, Strauss JF 3rd, Romero R, Chaiworapongsa T, Eschenbach DA, Buck GA, Jefferson KK. Identification of a gene in Mycoplasma hominis associated with preterm birth and microbial burden in intraamniotic infection. Am J Obstet Gynecol. 2015 Jun;212(6):779.e1-779.e13. doi: 10.1016/j.ajog.2015.01.032. Epub 2015 Jan 28. PubMed PMID: 25637842.

Fitting S, Ngwainmbi J, Kang M, Khan FA, Stevens DL, Dewey WL, Knapp PE, Hauser KF, Akbarali HI. Sensitization of enteric neurons to morphine by HIV-1 Tat protein. Neurogastroenterol Motil. 2015 Apr;27(4):468-80. doi: 10.1111/nmo.12514. Epub 2015 Feb 19. PubMed PMID: 25703354.

Ignatowska-Jankowska BM, Baillie GL, Kinsey S, Crowe M, Ghosh S, Owens RA, Damaj IM, Poklis J, Wiley JL, Zanda M, Zanato C, Greig IR, Lichtman AH, Ross RA. A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects. Neruopsychopharmacology. 2015 Dec;40(13):2948-59. doi: 10.1038/npp.2015.148. Epub 2015 Jun 8. PubMed PMID: 26052038.

Wiebelhaus JM, Grim TW, Owens RA, Lazenka MF, Sim-Selley LJ, Abdullah RA, Niphakis MJ, Vann RE, Cravatt BF, Wiley JL, Negus SS, Lichtman AH. Delta-9 tetrahydrocannabinol (THC) and endocannobinoid degradadtive enzyme inhibitors attenuate intracranial self-stimulation (ICSS) in mice. J Pharmacol Exp Ther. 2015 Feb;352(2): 195-207. doi: 10. 1124/jpet. 114.218677. Epub 2014 Nov 14. PubMed PMID: 25398241 PubMed Central PMCID: PMC4293433.

Ngwainmbi J, De DD, Smith TH, El-Hage N, Fitting S, Kang M, Dewey WL, Hauser KF, Akbarali HI. Effects of HIV-1 Tat on enteric neuropathogenesis. J Neurosci. 2014 Oct22;34(43): 14243-51. doi. 10. 1523/JNEUROSCI.2283-14.2014. PubMed PMID: 25339738; PubMed Central PMCID: PMC4205550.

Smith TH, Ngwainmbi J, Hashimoto A, Dewey WL, Akbarali HI. Morphine dependence in single enteric neurons from the mouse colon requires deletion of β-arrestin2. Physiol Rep. 2014 Sep4;2(9). pii: e12140. doi: 10. 14814/phy2.12140. Print 2014 Sep 1. PubMed PMID: 25194025; PMC4270231.

Ramesh D, Gamage TF, Vanustsel T, Owens RA, Abdullah RA, Niphakis MJ, Shea-Donohue T, Cravatt BF, Lichtman AH. Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice. Neuropsychopharmacology. 2013 May;38(6):1039-49. doi: 10.1038/npp.2012.269. Epub 2013 Jan 3. PubMed PMID: 23303065.

Smith TH, Ngwainmbi J, Grider JR, Dewey WL, Akbarali HI. An in-vitro preparation of isolated enteric neurons and glia from the myenteric plexus of the adult mouse. J. Vis Exp. 2013 aug 7;(78). doi: 10.3791/50688. PubMed PMID:23962959 PubMed Central PMCID: PMC3846983.

Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, Kinsey SG, Long JZ, Nomura DK, Sim-Selley LJ, Cravatt BF, Akbarali HI, Lichtman AH. Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. J Pharmacol Exp Ther. 2011 Oct;339(1):173-85. Epub 2011 Jun 30. PubMed PMID: 21719468; PubMed Central PMCID: PMC3186294.

PREP

Martin RK, Damle SR, Valentine YA, Zellner MP, James BN, et al. B1 Cell IgE Impedes Mast Cell-Mediated Enhancement of Parasite Expulsion through B2 IgE Blockade. Cell Rep. 2018 Feb 13;22(7):1824-1834. PubMed PMID: 29444434; NIHMSID; NIHMS943896; PubMed Central PMCID: PMC5832064.

Pagare PP, Ghatge MS, Musayev FN, Deshpande TM, Chen Q, et al. Rational design of pyridyl derivatives of vanillin for the treatment of sickle cell disease. Bioorg Med Chem. 2018 May 15;26(9):2530-2538. PubMed PMID: 29655608; NIHMSID: NIHMS959374; PubMed Central PMCID: PMC5935541.

Radcliff Z, Weaver P, Chen R, Streisand R, Holmes C. The Role of Authoritative Parenting in Adolescent Type 1 Diabetes Management. J Pediatr Psychol. 2018 Mar 1;43(2):185-194. PubMed PMID: 29048478; PubMed Central PMCID: PMC5896594.

Xu M, Obodo D, Yadavalli VK. The design, fabrication, and applications of flexible biosensing devices. Biosens Bioelectron. 2018 Oct 13;124-125:96-114. PubMed PMID: 30343162.

Montgomery J, Lu J, Ratliff S, Mezuk B. Food Insecurity and Depression Among Adults With Diabetes: Results From the National Health and Nutrition Examination Survey (NHANES). Diabetes Educ. 2017 Jun;43(3):260-217. PubMed PMID: 28436293; NIHMSID: NIHMS918966; PubMed Central PMCID: PMC5687057.

Allen-Daniels MJ, Serrano MG, Pflugner LP, Fettweis JM, Prestosa MA, et al. Identification of a gene in Mycoplasma hominis associated with preterm birth and microbial burden in intraamniotic infection. Am J Obstet Gynecol. 2015 Jun;212(6):779.e1-779.e13. PubMed PMID: 25637842; NIHMSID: NIHMS670245; PubMed Central PMCID: PMC4457590.

Beckta JM, Dever SM, Gnawali N, Khalil A, Sule A, et al. Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining. Oncotarget. 2015 Sep 29;6(29):27674-87. PubMed PMID: 26320175; PubMed Central PMCID: PMC4695017.

Caccavale LJ, Weaver P, Chen R, Streisand R, Holmes CS. Family Density and SES Related to Diabetes Management and Glycemic Control in Adolescents With Type 1 Diabetes. J Pediatr Psychol. 2015 Jun;40(5):500-8. PubMed PMID: 25596386; PubMed Central PMCID: PMC4447826.

Rahmani M, Aust MM, Benson EC, Wallace L, Friedberg J, et al. PI3K/mTOR inhibition markedly potentiates HDAC inhibitor activity in NHL cells through BIM- and MCL-1-dependent mechanisms in vitro and in vivo. Clin Cancer Res. 2014 Sep 15;20(18):4849-60. PubMed PMID: 25070836: NIHMSID: NIHMS617207; PubMed Central PMCID: PMC4166554.

Engeda J, Mezuk B, Ratliff S, Ning Y. Association between duration and quality of sleep and the risk of pre-diabetes: evidence from NHANES. Diabet. Med. 2013 Jun;30(6):676-80. PubMed PMID:23425048; NIHMSID: NIHMS449117; PubMed Central PMCID: PMC3660430.

West NW, Garcia-Vargas A, Chalfant CE, Park MA. OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2. BMC Cancer. 2013 May 24;13:256. PubMed PMID: 23706161; PubMed Central PMCID: PMC3674920.

White S, Acierno R, Ruggiero KJ, Koenen KC, Kilpatrick DG, et al. Association of CRHR1 variants and posttraumatic stress symptoms in hurricane exposed adults. J Anxiety Disord. 2013 Oct;27(7):678-83. PubMed PMID: 24077033; NIHMSID: NIHMS595629; PubMed Central PMCID: PMC4182958.

Asomaning N, Archer KJ. High-throughput DNA methylation datasets for evaluating false discovery rate methodologies. Comput Stat Data Anal. 2012 Jun 1;56(6):1748-56. Epub 2011 Oct 29. PubMed PMID: 22611297; NIHMSID: NIHMS336005; PubMed Central PMCID: PMC3352593.

Ramesh D, Ross GR, Schlosburg JE, Owens RA, Abdullah RA, et al. Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. J Pharmacol Exp Ther. 2011 Oct;339(1):173-85. Epub 2011 Jun 30. PubMed PMID: 21719468; PubMed Central PMCID: PMC3186294.

IRACDA

Damle SR, Martin RK, Cockburn CL, Lownik JC, Carlyon JA, Smith AD, Conrad DH. ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production. Allergy. 2018 Jan;73(1):125-136. doi: 10.1111/all.13261. Epub 2017 Aug 31. PubMed PMID: 28745029; PubMed Central PMCID: PMC5739941.

Hyer MM, Phillips LL, Neigh GN. Sex Differences in Synaptic Plasticity: Hormones and Beyond. Front Mol Neurosci. 2018 Jul 31;11:266. doi: 10.3389/fnmol.2018.00266. eCollection 2018. PubMed PMID: 30108482; PubMed Central PMCID: PMC6079238.

Beyer AR, Rodino KG, VieBrock L, Green RS, Tegels BK, Oliver LD Jr, Marconi RT, Carlyon JA. Orientia tsutsugamushi Ank9 is a multifunctional effector that utilizes a novel GRIP-like Golgi localization domain for Golgi-to-endoplasmic reticulum trafficking and interacts with host COPB2. Cell Microbiol. 2017 Jul;19(7). doi: 10.1111/cmi.12727. Epub 2017 Feb 3. PubMed PMID: 28103630; PubMed Central PMCID: PMC5469707.

Damle SR, Martin RK, Cross JV, Conrad DH. Macrophage migration inhibitory factor deficiency enhances immune response to Nippostrongylus brasiliensis. Mucosal Immunol. 2017 Jan;10(1):205-214. doi: 10.1038/mi.2016.29. Epub 2016 Apr 6. PubMed PMID: 27049059; PubMed Central PMCID: PMC5053838.

Lownik JC, Luker AJ, Damle SR, Cooley LF, El Sayed R, Hutloff A, Pitzalis C, Martin RK, El Shikh MEM, Conrad DH. ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. J Immunol. 2017 Oct 1;199(7):2305-2315. doi: 10.4049/jimmunol.1700833. Epub 2017 Aug 16. PubMed PMID: 28814605; PubMed Central PMCID: PMC5605448.

Nalli AD, Bhattacharya S, Wang H, Kendig DM, Grider JR, Murthy KS. Augmentation of cGMP/PKG pathway and colonic motility by hydrogen sulfide. AM J Physiol Gastrointest Liver Physiol. 2017 Oct 1;313(4):G330-G341. doi: 10.1152/ajpgi.00161.2017. Epub 2017 Jul 13. PubMed PMID: 28705807; PubMed Central PMCID: PMC5668569.

Ndaw VS, Abebayehu D, Spence AJ, Paez PA, Kolawole EM, Taruselli MT, Caslin HL, Chumanevich AP, Paranjape A, Baker B, Barnstein BO, Haque TT, Kiwanuka KN, Oskeritzian CA, Ryan JJ. TGF-β1 Suppresses IL-33-Induced Mast Cell Function. J Immunol. 2017 Aug 1;199(3):866-873. doi: 10.4049/jimmunol.1601983. Epub 2017 Jun 21. PubMed PMID: 28637902; PubMed Central PMCID: PMC5538185.

Rohrbach T, Maceyka M, Spiegel S. Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology. Crit Rev Biochem Mol Biol. 2017 Oct;52(5):543-553. doi: 10.1080/10409238.2017.1337706. Epub 2017 Jun 15. PubMed PMID: 28618839; PubMed Central PMCID: PMC5944845.

Crump KE, Oakley JC, Xia-Juan X, Madu TC, Devaki S, Mooney EC, Sahingur SE. Interplay of Toll-Like Receptor 9, Myeloid Cells, and Deubiquitinase A20 in Periodontal Inflammation. Infect Immun. 2016 Dec 29;85(1). pii: e00814-16. doi: 10.1128/IAI.00814-16. Print 2017 Jan. PubMed PMID: 27849177; PubMed Central PMCID: PMC5203663.

Crump KE, Sahingur SE. Microbial Nucleic Acid Sensing in Oral and Systemic Diseases. J Dent Res. 2016 Jan;95(1):17-25. doi: 10.1177/0022034515609062. Epub 2015 Oct 5. PubMed PMID: 26438211; PubMed Central PMCID: PMC4700663.

Kendig DM, Ets HK, Moreland RS. Effect of type II diabetes on male rat bladder contractility. Am J Physiol Renal Physiol. 2016 May 1;310(9):F909-22. doi: 10.1152/ajprenal.00511.2015. Epub 2016 Jan 28. PubMed PMID: 26823284; PubMed Central PMCID: PMC4867315.

Kendig DM, Hurst NR, Grider JR. Spatiotemporal Mapping of Motility in Ex Vivo Preparations of the Intestines. J Vis Exp. 2016 Jan 27;(107):e53263. doi: 10.3791/53263. PubMed PMID: 26863156; PubMed Central PMCID: PMC4781693.

Oki AT, Huang B, Beyer AR, May LJ, Truchan HK, Walker NJ, Galloway NL, Borjesson DL, Carlyon JA. Anaplasma phagocytophilum APH0032 Is Exposed on the Cytosolic Face of the Pathogen-Occupied Vacuole and Co-opts Host Cell SUMOylation.Front Cell Infect Microbiol. 2016 Sep 22;6:108. doi: 10.3389/fcimb.2016.00108. eCollection 2016. PubMed PMID: 27713867; PubMed Central PMCID: PMC5031783.

Beyer AR, VieBrock L, Rodino KG, Miller DP, Tegels BK, Marconi RT, Carlyon JA. Orientia tsutsugamushi Strain Ikeda Ankyrin Repeat-Containing Proteins Recruit SCF1 Ubiquitin Ligase Machinery via Poxvirus-Like F-Box Motifs. J Bacteriol. 2015 Oct;197(19):3097-109. doi: 10.1128/JB.00276-15. Epub 2015 Jul 13. PubMed PMID: 26170417; PubMed Central PMCID: PMC4560276.

Kendig DM, Grider JR. Serotonin and colonic motility. Neurogastroenterol Motil. 2015 Jul;27(7):899-905. doi: 10.1111/nmo.12617. PubMed PMID: 26095115; PubMed Central PMCID: PMC4477275.

McLeod JJ, Baker B, Ryan JJ. Mast cell production and response to IL-4 and IL-13. Cytokine. 2015 Sep;75(1):57-61. doi: 10.1016/j.cyto.2015.05.019. Epub 2015 Jun 15. PubMed PMID: 26088754; PubMed Central PMCID: PMC4532630.

Wahl SE, Kennedy AE, Wyatt BH, Moore AD, Pridgen DE, Cherry AM, Mavila CB, Dickinson AJ. The role of folate metabolism in orofacial development and clefting. Dev Biol. 2015 Sep 1;405(1):108-22. doi: 10.1016/j.ydbio.2015.07.001. Epub 2015 Jul 2. PubMed PMID: 26144049; PubMed Central PMCID: PMC4546841.

Crump KE, Bainbridge B, Brusko S, Turner LS, Ge X, Stone V, Xu P, Kitten T. The relationship of the lipoprotein SisaB, manganese and superoxide dismutase in Steptococcus sanguinis virulence for endocarditis. Mol Microbiol. 2014 Jun;92(6):1243-59. doi: 10.1111/mmi.12625. Epub 2014 May 12. PubMed PMID: 24750294; PubMed Central PMCID: PMC4070010.

Faber TW, Pullen NA, Fernando JF, Kolawole EM, McLeod JJ, Taruselli M, Williams KL, Rivera KO, Barnstein BO, Conrad DH, Ryan JJ. ADAM10 is required for SCF-induced mast cell migration. Cell Immunol. 2014 Jul;290(1):80-8. doi: 10.1016/j.cellimm.2014.05.005. Epub 2014 May 21. PubMed PMID: 24950026; PubMed Central PMCID: PMC4128322.

Martin RK, Saleem SJ, Folgosa L, Zellner HB, Damle Sr, Nguyen GK, Ryan JJ, Bear HD, Irani AM, Conrad DH. Mast cell histamine promotes the immunoregularity activity of myeloid-derived suppressor cells. J Leukoc Biol. 2014 Jul;96(1):151-9. doi: 10.1189/jlb.5A1213-644R. Epub 2014 Mar 7. PubMed PMID: 24610880; PubMed Central PMCID: PMC4056279.

Morales JK, Saleem SJ, Martin RK, Saunders BL, Barnstein BO, Faber TW, Pullen NA, Kolawole EM, Brooks KB, Norton SK, Sturgill J, Graham L, Bear HD, Urban JF, Lantz CS, Conrad DH, Ryan JJ. Myeloid-derived supressor cells enhance IgE-mediated mast cell repsonses. J Leukoc Biol. 2014 Apr;95(4):643-50. doi: 10.1189/jlb.0913510. Epub 2013 Dec 12. PubMed PMID: 24338630; PubMed Central PMCID: PMC3958743.

Rhodes DV, Crump KE, Makhlynets O, Snyder M, Ge X, Xu P, Stubbe J, Kitten T. Genetic characterization and role in virulence of the ribonucleotide reductases of Streptococcus sanguinis. J Biol Chem. 2014 Feb 28;289(9):6273-87. doi: 10.1074/jbc.M113.533620. Epub 2013 Dec 31. PubMed PMID: 24381171; PubMed Central PMCID: PMC3937693.

Fernando J, Faber TW, Pullen NA, Falanga YT, Kolawole EM, Oskertizian CA, Barnstein BO, Bandara G, Li G, Schwartz LB, spiegel S, Strauss DB, Conrad DH, Bunting KD, Ryan JJ. Genotype-dependent effect of TGF-β1 on mast cell function: targeting the Stat5 pathway. J Immunol. 2013 Nov 1;191(9):4505-13. doi: 10.4049/jimmunol.1202723. Epub 2013 Sep 25. PubMed PMID:24068671; PubMed Central PMCID: PMC3846427.

Garg K, Pullen NA, Oskeritzian CA, Ryan JJ, Bowlin GL. Macrophage funcitional polarization (M1/M2) in repsonse to varying fiber and pore dimensions of electrospun scaffolds. Biomaterials. 2013 Jun;34(18):4439-51. doi: 10.1016/j.biomaterials.2013.02.065. Epub 2013 Mar 17. PubMed PMID: 23515178; PubMed Central PMCID: PMC3623371.

Makhlynets O, Boal AK, Rhodes DV, Kitten T, Rosenzweig AC, Stubbe J. Streptococcus sanguinis class lb ribonucleotide reductase: high activity with both iron and manganese cofactors and structural insights. J Biol Chem. 2014 Feb 28;289(9):6259-72. doi: 10.1074/jbc.M113.533554. Epub 2013 Dec 31. PubMed PMID: 24381172; PubMed Central PMCID: PMC3937692.

Das SK, Bhutia SK, Kegelman TP, Peachy L, Oyesanya RA, Dasgupta S, Sokhi UK, Azab B, Dash R, Quinn BA, Kim K, Barral PM, Su ZZ, Boukerche H, Sarkar D, Fisher PB. MDA-9/syntenin: a positive gatekeeper of melanoma metastasis. Front Biosci (Landmark Ed). 2012 Jan 1;17:1-15. PubMed PMID: 22201728.

Falanga YT, Chaimowitz NS, Charles N, Finkelman FD, Pullen NA, Barbour S, Dholaria K, Faber T, Kolawole M, Huang B, Odom S, Rivera J, Carlyon J, Conrad DH, Spiegel S, Oskeritzian CA, Ryan JJ. Lyn but not Fyn kinase controls IgG-mediated systemic anaphylaxis.J Immunol. 2012 May 1;188(9):4360-8. doi: 10.4049/jimmunol.1003223. Epub 2012 Mar 26. PubMed PMID: 22450804; PubMed Central PMCID: PMC3536057.

Golding SE, Pullen NA, Lama Tamang TD, Hubbard NM, Bulluck LP, Johnson AA, Smith-Mason J, Hill HH, and Barbour SE. "Undergraduate Research Training Blossoms at VCU: Pollinated by Students, Nurtured by Faculty."CUR Quarterly, Forthcoming: Fall 2012 vol.33.

Hedvat M, Emdad L, Das SK, Kim K, Dasgupta S, Thomas S, Hu B, Zhu S, Dash R, Quinn BA, Oyesanya RA, Kegelamn TP, Sokhi UK, Sarkar S, Erdogan E, Menezes ME, Bhoopathi P, Wang XY, Pomper MG, Wei J, We B, Stebbins JL, Diaz PW, Reed JC, Pellecchia M, Sarkkar D, Fisher PB. Selected approaches for rational drug design and hgh throughput screening to identify anticancer molecules. Anticancer Agents Med Chem. 2012 Nov;12(9):1143-55. PubMed PMID: 22931411; PubMed Central PMCID: PMC3763986.

Pullen NA, Barnstein BO, Falanga YT, Wang Z, Suzuki R, Tamang TD, Khurana MC, Harry EA, Draber P, Bunting KD, Mizuno K, Wilson BS, Ryan JJ. Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production. J Biol Chem. 2012 Jan 13;287(3):2045-54. doi: 10.1074/jbc.M111.311142. Epub 2011 Nov 30. PubMed PMID: 22130676; PubMed Central PMCID: PMC3265884.

Pullen NA, Falanga YT, Morales JK, Ryan JJ. The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling. Front Immunol. 2012 May 11;3:117. doi: 10.3389/fimmu.2012.00117. eCollection 2012. PubMed PMID: 22593761; PubMed Central PMCID: PMC3350083.

Kabolizadeh P, Engelmann BJ, Pullen N, Stewart JK, Ryan JJ, Farrell NP. Platinum anticancer agents and antidepressants: desipramine enhances platinum-based cytotoxicity in human colon cancer cells.J Biol Inorg Chem. 2012 Jan;17(1):123-32. doi: 10.1007/s00775-011-0836-1. Epub 2011 Sep 15. PubMed PMID: 21918844; PubMed Central PMCID: PMC3250067.

Quinn BA, Dash R, Azab B, Sarkar S, Das SK, Kumar S, Oyesanya RA, Dasgupta S, Dent P, Grant S, Rahmani M, Curiel DT, Dmitriev I, Hedvat M, Wei J, Wu B, Stebbins JL, Reed JC, Pellecchia M, Sarkar D, Fisher PB. Targeting Mcl-1 for the therapy of cancer. Expert Opin Investig Drugs. Expert Opin Investig Drugs. 2011 Oct;20(10):1397-411. doi: 10.1517/13543784.2011.609167. Epub 2011 Aug 19. PubMed PMID: 21851287; PubMed Central PMCID: PMC3205956.

MARC

Tsotsoros SD, Lutz PB, Daniel AG, Peterson EJ, de Paiva REF, Rivera E, Qu Y, Bayse CA, Farrell NP. Enhancement of the physicochemical properties of [Pt(dien)(nucleobase)]2+ for HIVNCp7 targeting. Chem Sci. 2017 Feb 1;8(2):1269-1281. doi: 10.1039/c6sc03445d. Epub 2016 Oct 6. PubMed PMID: 28451269; PubMed Central PMCID: PMC5369524.

Aduba DC Jr, Overlin JW, Frierson CD, Bowlin GL, Yang H. Electrospinning of PEGylated polyamidoamine dendrimer fibers. Mater Sci Eng C Mater Biol Appl. 2015 Nov 1;56:189-94. doi: 10.1016/j.msec.2015.06.025. Epub 2015 Jun 14. PubMed PMID: 26249580; PubMed Central PMCID: PMC4552351.

Mathies LD, Blackwell GG, Austin MK, Edwards AC, Riley BP, Davies AG, Bettinger JC. SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3032-7. doi: 10.1073/pnas.1413451112. Epub 2015 Feb 23. PubMed PMID: 25713357; PubMed Central PMCID: PMC4364201.

Lizhanyak PN, Yohannes H, Ottens AK. Neuroproteome Dynamics in Modeled Brain Injury: A Systems Neurobiology Perspective. In: Kobeissy FH, editor. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects. Boca Raton (FL): CRC Press/Taylor & Francis; 2015. Chapter 27. PubMed PMID: 26269918.

Kim EY, Sturgill JL, Hait NC, Avni D, Valencia EC, Maceyka M, Lima S, Allegood J, Huang WC, Zhang S, Milstien S, Conrad D, Spiegel S. Role of sphingosine kinase 1 and sphingosine-1-phosphate in CD40 signaling and IgE class switching. FASEB J. 2014 Oct;28(10):4347-58. doi: 10.1096/fj.14-251611. Epub 2014 Jul 1. PubMed PMID: 25002116; PubMed Central PMCID: PMC4202100.

Cruickshanks N, Hamed HA, Booth L, Tavallai S, Syed J, Sajithlal GB, Grant S, Poklepovic A, Dent P. Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy. Cancer Biol Ther. 2013 Oct 1;14(10):982-96. doi: 10.4161/cbt.26234. Epub 2013 Aug 22. PubMed PMID: 24025251; PubMed Central PMCID: PMC3926895.

Sajithlal GB, Hamed HA, Cruickshanks N, Booth L, Tavallai S, Syed J, Grant S, Poklepovic A, Dent P. Sorafenib/regorafenib and phosphatidyl inositol 3 kinase/thymoma viral proto-oncogene inhibition interact to kill tumor cells. Mol Pharmacol. 2013 Oct;84(4):562-71. doi: 10.1124/mol.113.088005. Epub 2013 Jul 22. PubMed PMID: 23877009; PubMed Central PMCID: PMC3781387.

Fuller BF, Cortes DF, Landis MK, Yohannes H, Griffin HE, Stafflinger JE, Bowers MS, Lewis MH, Fox MA, Ottens AK. Exposure of rats to environmental tobacco smoke during cerebellar development alters behavior and perturbs mitochondrial energetics. Environ Health Perspect. 2012 Dec;120(12):1684-91. doi: 10.1289/ehp.1104857. Epub 2012 Sep 26. PubMed PMID: 23014793; PubMed Central PMCID: PMC3548280.

Pullen NA, Barnstein BO, Falanga YT, Wang Z, Suzuki R, Tamang TD, Khurana MC, Harry EA, Draber P, Bunting KD, Mizuno K, Wilson BS, Ryan JJ. Novel mechanism for Fc{epsilon}RI-mediated signal transducer and activator of transcription 5 (STAT5) tyrosine phosphorylation and the selective influence of STAT5B over mast cell cytokine production. J Biol Chem. 2012 Jan 13;287(3):2045-54. Epub 2011 Nov 30. PubMed PMID: 22130676; PubMed Central PMCID: PMC3265884.

Bareford MD, Park MA, Yacoub A, Hamed HA, Tang Y, Cruickshanks N, Eulitt P, Hubbard N, Tye G, Burow ME,Fisher PB, Moran RG, Nephew KP, Grant S, Dent P. Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells. Cancer Res. 2011 Jul 15;71(14):4955-67. PubMed PMID: 21622715; PubMed Central: PMC3139015.

Mitchell C, Hamed HA, Cruickshanks N, Tang Y, Bareford MD, Hubbard N, Tye G, Yacoub A, Dai Y, Grant S, Dent P. Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death. Cancer Biol Ther. 2011 Aug 1;12(3):215-28. PubMed PMID: 21642769; PubMed Central PMCID: PMC3230482.

STEP-UP

Drake JI, Bogaard HJ, Mizuno S, Clifton B, Xie B, Gao Y, Dumur CI, Fawcett P, Voelkel NF, Natarajan R. Molecular Signature of a Right Heart Failure Program in Chronic Severe Pulmonary Hypertension. Am J Respir Cell Mol Biol. 2011 Dec;45(6):1239-47. doi: 10.1165/rcmb.2010-0412OC. Epub 2011 Jun 30. PubMed PMID: 21719795; PubMed Central PMCID: PMC3361357.

King AL, Gehr T, Cotterell A, Posner M, Mas V. MicroRNA profiles in allograft tissues and paired urines associate with chronic allograft dysfunction with IF/TA. Am J Transplant. 2011 Oct; 11(10):2110-22. doi: 10.1111/j.1600-6143.2011.03666.x. Epub 2011 Jul 27. PubMed PMID: 21794090; PubMed Central PMCID: PMC3184368.

Mas VR, Scian MJ, Archer KJ, Suh JL, David KG, Ren Q, Gehr TW, King AL, Posner MP, Mueller TF, Maluf DG. Pretransplant transcriptome profiles identify among kidneys with delayed graft function those with poorer quality and outcome. Mol Med. 2011 Sep 6. doi: 10.2119/molmed.2011.00159. Epub 2011 Sep 6. PubMed PMID: 21912807; PubMed Central PMCID: PMC3321827.